Which type of cells do NOT have center-surround receptive fields?

Horizontal cells do not have center-surround receptive fields. Unlike bipolar and ganglion cells, which exhibit this organization allowing them to perform spatial contrast processing, horizontal cells primarily function to integrate signals from multiple photoreceptor cells. They play a key role in lateral inhibition, helping to ensure that visual information processed by the bipolar cells translates effectively to contrast in the ganglion cell responses.

The center-surround organization is vital for detecting edges and contrasts in visual stimuli, a mechanism primarily observed in cells like ganglion cells in the retina and various types of cells in the lateral geniculate nucleus (LGN). However, horizontal cells do not conform to this receptive field arrangement; instead, they modulate the signals from photoreceptors through their connections to the bipolar cells, allowing for the summation of inputs but lacking the specific center-surround configuration characteristic of other cell types involved in detecting spatial information.