Which statement about intraocular pressure (IOP) is NOT true?

Intraocular pressure (IOP) indeed varies throughout the day, and this diurnal variation is a well-documented physiological phenomenon. The highest levels of IOP are typically observed in the early morning hours, not specifically during nocturnal hours as a fixed characteristic. Therefore, it is not accurate to assert that IOP is highest during the nocturnal hours without considering the full context of time-based fluctuations.

Moreover, IOP is generally influenced by a variety of factors, including the individual’s circadian rhythm, fluid dynamics within the eye, and changes in scleral tension. These factors cause IOP to peak at different times for different individuals, emphasizing the dynamic nature of IOP throughout a 24-hour cycle.

Additionally, it is known that individuals with glaucoma can experience more pronounced diurnal variation in their IOP compared to individuals without this condition. This variability can affect diagnosis and management. Corneal thickness also plays a significant role in the measurement of IOP, as thicker corneas can provide higher IOP readings, while thinner corneas may lead to an underestimation of true IOP.

Therefore, the statement regarding IOP being highest during nocturnal hours lacks precision and does not align with the established understanding of its physiological behavior.