Which of the following statements about meibomian glands is NOT true?

The statement regarding the secretion method of meibomian glands is not true because meibomian glands secrete their product, meibum, through a holocrine secretion mechanism, not apocrine secretion. In holocrine secretion, the entire cell disintegrates to release its contents, whereas in apocrine secretion, only a portion of the cell is shed. This distinction is important because it directly affects the composition and properties of the lipid layer of the tear film.

The other statements about the meibomian glands are accurate. Specifically, the number of glands located in the upper and lower tarsal plates is well-documented, with approximately 25 situated in the upper tarsal plate and around 20 in the lower tarsal plate. Additionally, the function of these glands in secreting the lipid layer of the tear film is crucial, as this layer helps to minimize tear evaporation and maintain ocular surface homeostasis.