Which layer of V1 is primarily responsible for receiving visual input from the LGN?

The primary visual cortex (V1) is organized into six distinct layers, each with specific functions and connections. Layer 4 of V1 is particularly notable for its role in processing incoming visual information. This layer receives direct input from the lateral geniculate nucleus (LGN), which is crucial for the initial stages of visual perception.

Layer 4 can be subdivided into layers 4A, 4B, and 4C, with the most prominent projections from the LGN terminating in layer 4C. This layer acts as a primary recipient of the visual signals relayed from the LGN, where they begin to undergo processing that contributes to the perception of spatial and temporal aspects of vision.

The specialization of layer 4 for this function underscores its importance in the hierarchy of visual processing in the cortex, allowing further integration and interpretation of visual information as it ascends through the cortical layers. As visual signals are processed, they are relayed to other layers for additional processing, but their initial reception occurs in layer 4. Consequently, this layer plays a crucial role in the visual pathway, acting as a foundational layer for the integration of visual stimuli.