Which aspect of aqueous humor is significantly affected by changes in intraocular pressure?

The volume of aqueous humor is significantly affected by changes in intraocular pressure because the production and drainage of aqueous humor are closely regulated processes that maintain eye health and intraocular pressure stability. The ciliary body produces aqueous humor, which then flows through the pupil into the anterior chamber and drains through the trabecular meshwork and Schlemm's canal.

When intraocular pressure increases, it often indicates a disruption in the outflow of aqueous humor, leading to an increase in its volume within the eye. Conversely, if intraocular pressure decreases, the volume of aqueous humor may also decrease due to improved drainage or reduced production. This relationship is crucial for maintaining the overall homeostasis of the eye, as both excessive and insufficient aqueous humor can lead to ocular conditions such as glaucoma.

Viscosity, temperature, and pH of aqueous humor do not experience significant direct changes as a result of variations in intraocular pressure; these parameters are relatively stable under normal physiological conditions and influenced more by metabolic processes and homeostatic mechanisms rather than acute changes in pressure. Therefore, emphasizing volume clarifies how intraocular dynamics are intrinsically linked to aqueous humor management.