In which layer of the retina will you primarily see dot/blot hemes?

Dot and blot hemorrhages are typically associated with conditions that affect the inner layers of the retina, particularly the inner nuclear layer. This layer is where the cell bodies of bipolar cells, horizontal cells, and some amacrine cells reside. When there is

damage or disruption to the retinal vasculature, as seen in conditions like diabetic retinopathy or hypertension, bleeding may occur in this area, leading to the presence of dot/blot hemes.

The retinal nerve fiber layer is less likely to show dot/blot hemorrhages; instead, any hemorrhages here would typically present as larger, more linear flame-shaped hemorrhages due to the orientation of the nerve fibers. The outer nuclear layer, where photoreceptors' cell bodies reside, does not typically exhibit these types of hemorrhages. Lastly, the photoreceptor layer primarily contains the light-sensitive cells, and while it can also be affected by various retinal diseases, it is not the layer where dot/blot hemes are observed. Thus, the inner nuclear layer is the primary location for these types of retinal hemorrhages.